For men experiencing symptoms of hormonal imbalance or those interested in optimizing their health, regular hormone monitoring can provide valuable insights. Additional tests may include prolactin levels, thyroid function tests, and imaging studies of the pituitary gland if secondary causes are suspected. Because hormone levels can fluctuate, providers often recommend repeat testing to confirm initial results. As men age, testosterone production naturally declines while LH levels often increase. In secondary hypogonadism, both LH and testosterone levels are typically low because the signaling system itself is impaired.
A special group of hormones called androgens affects hair growth. If they’re consistently high or low, you may experience unpleasant symptoms worth discussing with your provider. Testosterone is an essential part of reproductive health.
In primary hypogonadism, LH levels are typically elevated as the pituitary gland attempts to stimulate underperforming gonads. Hypogonadism occurs when the gonads (testes in men and ovaries in women) produce insufficient sex hormones. Similarly, in men, abnormal LH levels can signal conditions such as hypogonadism or pituitary disorders. Elevated LH levels in women may indicate menopause, while low levels could suggest issues with the pituitary gland or hypothalamus. Low LH levels in men can lead to reduced testosterone production, resulting in symptoms such as fatigue, low libido, and infertility. It stimulates Leydig cells in the testes to produce testosterone, which is crucial for sperm production and overall male reproductive health. Healthcare providers typically measure LH levels through a blood test, commonly referred to as an LH hormone test.
Furthermore, the potential of LH in assisted reproductive technologies for improving sperm quality is discussed. LH stimulates testosterone synthesis in LCs, which is critical for maintaining spermatogenesis and male fertility. His latest book, ‘Lies I Taught In Medical School’ is an instant New York Times bestseller and has re-framed how we think about metabolic health and longevity.
The severity and combination of symptoms can vary significantly between individuals. Discover biomarkers that predict healthy aging and add years to your life. This age-related change, sometimes called andropause or late-onset hypogonadism, reflects the testes' decreased responsiveness to LH stimulation. Other genetic conditions affecting testicular development or function, such as Y chromosome microdeletions or androgen insensitivity syndrome, can also result in high LH levels. Klinefelter syndrome, a genetic condition where males have an extra X chromosome (XXY), is a common cause of primary hypogonadism and elevated LH. Varicoceles, which are enlarged veins in the scrotum, can also affect testicular function and lead to elevated LH levels. Physical damage to the testes from injury, surgery, or radiation therapy can impair their ability to produce testosterone.
As of 2025, it’s not yet approved for males who naturally experience a decline in testosterone as they age. Thirteen women were studied from the United States Women's Water Polo Team. Thirty-one women runners were included in this study, and each woman served as her own control.
The symptoms of low testosterone vary based on your age. In female adults, high levels of testosterone may be a sign of polycystic ovary syndrome (PCOS). High levels of testosterone in female infants may lead to enlargement of their clitoris that can look almost like a penis. Your provider will always reference your laboratory’s normal ranges when interpreting your results. (LH more often stimulates the production of estrogen and progesterone in ovaries.) LH then travels to your gonads and stimulates the production and release of testosterone.

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